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Prescription Diabetes Drugs
Diabetes and High Blood Pressure - Is Insulin Resistance the Culprit?
Posted by admin in Prescription Diabetes Drugs, Weight Loss on April 28th, 2009
Expired medications are commonplace and inertia notwithstanding, many of us tend to rely on an intuitive sense of their value in continuing to store and use them. Such drugs can be harmful to health in several ways; they can be unpredictable in effectiveness, simply ineffective, or even toxic.
The formal way of classifying a medication as having expired is through it’s labeled expiry date. This date is often set based on a combination of the common properties of the dosage form as well as the stability and expiration studies of the product that have been conducted by the manufacturer. Importantly, this expiry date is contingent on specific storage conditions of the product. Although a medication may pass it’s labeled expiry date, it may not necessarily be any less effective or dangerous to consume depending on the product itself, the storage conditions and the circumstances leading up to expiry.
When most medications pass their expiry date under appropriate storage conditions, they are generally taken to have become so variable in effectiveness as to have become unsuitable for use. This often comes about as a result of the degradation of the active ingredients of the medication with exposure to physical, chemical or microbiological variables like temperature, pressure, humidity, light, bacteria as well as other components of the product known as excipients.
Creams may “crack” once their expiry date is passed, leading to a separation of the components and hence provide a non-uniform delivery of active ingredients. This can lead to the poor control of conditions like eczema or acne. Tablet medications can mechanically “powder” off, change in consistency with exposure to water vapor or even experience the contained drug itself becoming ineffective on prolonged exposure to air as occurs with glyceryl trinitrate, an emergency medicine that can easily become ineffective in relieving acute symptoms of chest pain. With common injections, should the acidity change to fall outside a fairly narrow range, significant pain and tissue damage can result from use. With most eye drops, an expiry date of one month after opening is accepted to minimize the potential for dangerous bacterial contamination.
With any medication, once a specific threshold of remaining active ingredient is passed, the medication can no longer be relied upon to deliver accurate doses. This loss of reliability is often exacerbated by the fact that the active ingredients can degrade into various combinations of active, inactive or toxic breakdown products. The common aspirin is for instance, known to react with moisture to breakdown into salicylic acid, which is active, and acetic acid, which is inactive and can lead to toxicity in excess.
While the expiry date provides a useful gauge of when to stop using a medication, there are also many other factors that can informally accelerate the expiry of a medication and make it dangerous to use, chief among which is how the medication is stored. It is oftentimes not just the medication that is affected by storage conditions but also the storage container. Under inappropriate storage conditions, certain containers can leech material into liquid medication preparations, or medication particles can stick to the container rather than remain separated. On average, a 10 degree rise in temperature doubles the rate of chemical reactions that occur to a medication product and can accelerate the rate of bacterial contamination several fold. Just like an ice cream can simply melt or a loaf of bread becomes mouldy much quicker if not refrigerated, many medication products can easily expire much faster when not stored appropriately.
With oral liquid and topical medications, potentially dangerous changes associated with expiry can at times be detected by color or consistency changes, component separations, altered smell or taste (oral preparations). Should a suspicion of expiry arise, a medication expert should be consulted regardless of whether or not the labeled expiry date has been passed.
“Expiry” should also be understood to occur once a supply of medications is no longer used appropriately for it’s intended purpose. Consultation with a medication expert is always advised to prevent the inappropriate use of existing medication supplies. Inappropriate use can often occur with self-medication and is harmful. An unfinished supply of a previously used antibiotic may be tried to treat a new infection that is actually untreatable by or resistant to that antibiotic. This practice may not only delay recovery but can also encourage the proliferation of “super bugs” that have resistance to many antibiotics. Another incorrect purpose involves sharing medications and this can be especially harmful if another is allergic to the shared medication or a child or pet is medicated with an adult’s medication. Children often require dose adjustments to accommodate their size while many human drugs are often unsuitable for pets. Even a simple food like chocolate that we may enjoy can easily be toxic to a pet dog.
Another mechanism whereby medication expiry is dangerous occurs when an unfinished supply is used despite new information that points to increased precautions associated with the medication or that has led to it’s recall. An example is obtaining pain relief from a previous supply of a painkiller like Vioxx (rofecoxib) or Celebrex (celecoxib) in spite of an existing heart condition that is now known to relate to an increased risk of fatality under those circumstances of consumption.
Expired medications that are kept instead of discarded not only take up space but can actually discourage the appropriate use of new supplies in the treatment of illness. A medication cabinet, if not tended to regularly, could eventually contain more expired medications than viable ones and this can lead to the accidental consumption of an expired medication in place of a viable one. It is definitely advisable to clear the medication cabinet of expired medicaitons at least annually if not more often.
A further danger however, lies in how expired medications are disposed of. Expired medications and pharmaceutical byproducts can be harmful to the environment especially when they end up in our rivers and drinking water supply. Hormonal compounds like estrogen from birth control pills and patches as well as antibiotics have been linked to being flushed by individuals and institutions into sewage, draining largely unchanged and collecting in rivers and streams, then returning in tiny amounts into drinking water. Traces of antibiotics could worsen bacterial resistance while estrogens and other steroids are known to change the reproductive characteristics of fish. Even trace amounts of chemotherapy medications have emerged in tap water and this could be severely detrimental to the unborn babies of pregnant women who drink such water. The long-term impact on human health of medications in our rivers and drinking water is as yet unknown but no one would want to wait to find out. We can all play our part by inquiring on and using pharmacy or state-run programs for the disposal of expired medications instead of sending them down the sink or the toilet bowl.
A pharmacist is the expert of choice to approach in handling medication expiry and should be consulted if in doubt. As a general rule, it is always best to safeguard your own health and that of those around you by expeditiously and appropriately discarding all expired medications.
What's Up Sugar, Are You Refined?
Posted by admin in Prescription Diabetes Drugs, Weight Loss on April 28th, 2009
Expired medications are commonplace and inertia notwithstanding, many of us tend to rely on an intuitive sense of their value in continuing to store and use them. Such drugs can be harmful to health in several ways; they can be unpredictable in effectiveness, simply ineffective, or even toxic.
The formal way of classifying a medication as having expired is through it’s labeled expiry date. This date is often set based on a combination of the common properties of the dosage form as well as the stability and expiration studies of the product that have been conducted by the manufacturer. Importantly, this expiry date is contingent on specific storage conditions of the product. Although a medication may pass it’s labeled expiry date, it may not necessarily be any less effective or dangerous to consume depending on the product itself, the storage conditions and the circumstances leading up to expiry.
When most medications pass their expiry date under appropriate storage conditions, they are generally taken to have become so variable in effectiveness as to have become unsuitable for use. This often comes about as a result of the degradation of the active ingredients of the medication with exposure to physical, chemical or microbiological variables like temperature, pressure, humidity, light, bacteria as well as other components of the product known as excipients.
Creams may “crack” once their expiry date is passed, leading to a separation of the components and hence provide a non-uniform delivery of active ingredients. This can lead to the poor control of conditions like eczema or acne. Tablet medications can mechanically “powder” off, change in consistency with exposure to water vapor or even experience the contained drug itself becoming ineffective on prolonged exposure to air as occurs with glyceryl trinitrate, an emergency medicine that can easily become ineffective in relieving acute symptoms of chest pain. With common injections, should the acidity change to fall outside a fairly narrow range, significant pain and tissue damage can result from use. With most eye drops, an expiry date of one month after opening is accepted to minimize the potential for dangerous bacterial contamination.
With any medication, once a specific threshold of remaining active ingredient is passed, the medication can no longer be relied upon to deliver accurate doses. This loss of reliability is often exacerbated by the fact that the active ingredients can degrade into various combinations of active, inactive or toxic breakdown products. The common aspirin is for instance, known to react with moisture to breakdown into salicylic acid, which is active, and acetic acid, which is inactive and can lead to toxicity in excess.
While the expiry date provides a useful gauge of when to stop using a medication, there are also many other factors that can informally accelerate the expiry of a medication and make it dangerous to use, chief among which is how the medication is stored. It is oftentimes not just the medication that is affected by storage conditions but also the storage container. Under inappropriate storage conditions, certain containers can leech material into liquid medication preparations, or medication particles can stick to the container rather than remain separated. On average, a 10 degree rise in temperature doubles the rate of chemical reactions that occur to a medication product and can accelerate the rate of bacterial contamination several fold. Just like an ice cream can simply melt or a loaf of bread becomes mouldy much quicker if not refrigerated, many medication products can easily expire much faster when not stored appropriately.
With oral liquid and topical medications, potentially dangerous changes associated with expiry can at times be detected by color or consistency changes, component separations, altered smell or taste (oral preparations). Should a suspicion of expiry arise, a medication expert should be consulted regardless of whether or not the labeled expiry date has been passed.
“Expiry” should also be understood to occur once a supply of medications is no longer used appropriately for it’s intended purpose. Consultation with a medication expert is always advised to prevent the inappropriate use of existing medication supplies. Inappropriate use can often occur with self-medication and is harmful. An unfinished supply of a previously used antibiotic may be tried to treat a new infection that is actually untreatable by or resistant to that antibiotic. This practice may not only delay recovery but can also encourage the proliferation of “super bugs” that have resistance to many antibiotics. Another incorrect purpose involves sharing medications and this can be especially harmful if another is allergic to the shared medication or a child or pet is medicated with an adult’s medication. Children often require dose adjustments to accommodate their size while many human drugs are often unsuitable for pets. Even a simple food like chocolate that we may enjoy can easily be toxic to a pet dog.
Another mechanism whereby medication expiry is dangerous occurs when an unfinished supply is used despite new information that points to increased precautions associated with the medication or that has led to it’s recall. An example is obtaining pain relief from a previous supply of a painkiller like Vioxx (rofecoxib) or Celebrex (celecoxib) in spite of an existing heart condition that is now known to relate to an increased risk of fatality under those circumstances of consumption.
Expired medications that are kept instead of discarded not only take up space but can actually discourage the appropriate use of new supplies in the treatment of illness. A medication cabinet, if not tended to regularly, could eventually contain more expired medications than viable ones and this can lead to the accidental consumption of an expired medication in place of a viable one. It is definitely advisable to clear the medication cabinet of expired medicaitons at least annually if not more often.
A further danger however, lies in how expired medications are disposed of. Expired medications and pharmaceutical byproducts can be harmful to the environment especially when they end up in our rivers and drinking water supply. Hormonal compounds like estrogen from birth control pills and patches as well as antibiotics have been linked to being flushed by individuals and institutions into sewage, draining largely unchanged and collecting in rivers and streams, then returning in tiny amounts into drinking water. Traces of antibiotics could worsen bacterial resistance while estrogens and other steroids are known to change the reproductive characteristics of fish. Even trace amounts of chemotherapy medications have emerged in tap water and this could be severely detrimental to the unborn babies of pregnant women who drink such water. The long-term impact on human health of medications in our rivers and drinking water is as yet unknown but no one would want to wait to find out. We can all play our part by inquiring on and using pharmacy or state-run programs for the disposal of expired medications instead of sending them down the sink or the toilet bowl.
A pharmacist is the expert of choice to approach in handling medication expiry and should be consulted if in doubt. As a general rule, it is always best to safeguard your own health and that of those around you by expeditiously and appropriately discarding all expired medications.
Onset Diabetes Symptoms - What Are They and How Can I Avoid Diabetes
Posted by admin in Prescription Diabetes Drugs, Weight Loss on April 28th, 2009
What is Onset Diabetes?
Onset Diabetes, otherwise known as Type 2 Diabetes, is when you have high levels of sugar (glucose) in the bloodstream which spills over into the urine. Most times diabetes is associated with high amounts of carbohydrates in the diet.
Of all the non-insulin dependent diabetics, 90% can be “cured” by achieving their ideal weight and maintaining healthy eating habits.
What are the symptoms of diabetes?
- blurry vision
- increased tiredness or fatigue
- slow healing of wounds or infection
- increasingly high thirst
- frequent need to urinate
- increase in appetite
- impotence
How do they test for diabetes?
Your doctor will test you for diabetes by checking your blood sugar (glucose) level through a sample of your blood. If your blood sugar level is above 126, the doctor will ask you to come back for a re-test. If the second time your blood sugar level is above 126, your diagnosis will most likely be diabetes. A blood sugar that immediately comes back above 200 will instantly be labeled onset diabetes.
How can I Avoid Diabetes?
Prevention is always the best way to avoid any disease. But with onset diabetes, watching what you eat as well as exercising is the best way to control this deadly disease.
A diet with very little or no sugar and complex carbohydrates is best. Some examples of foods to avoid would be candy, boxed cereal, alcohol, soda/pop, pizza, ice cream, cookies, white bread (whole wheat is the best choice) and honey.
Try to stay away from pastries, pasta and sugary drinks. Although you can have these in moderation, it is best to avoid them altogether.
Finding Cheap Glucose Meters
Posted by admin in Prescription Diabetes Drugs, Weight Loss on April 28th, 2009
You wake up and reach for your glucose meter to see what you can have for breakfast. You are running late for work, only to remember you forgot your glucose meter outside and must go back and get it. You would love to be able to quit your job and work for yourself, but you need the insurance. You go to a friend’s dinner party, and checking your sugar you find that you must forego even a small taste of the dessert that’s being offered. And then you come home to find most the mail you got for the day was medical bills. That’s life as a diabetic. Wouldn’t it be nice to have a break somehow? In this article, I am going to give you some tips on finding cheap glucose meters.
There is a lot of good information about finding cheap glucose meters available on the internet. A lot of people prefer to order their supplies online because it is very convenient, and is often less expensive. Look for website reviews to make sure that the products are good quality. Glucose meters themselves are something that you do not need to purchase often, but kits may include meters, strips, and other supplies you will need.
If you have insurance, research what your provider will cover. You may be surprised to complete what all is taken care of for you.
Buying cheap glucose meters in quantity is another way to help lower your costs. Meet with your doctor and see what you need, and then just buy those products.
Go to the local health fairs and see what they have available. You should also check with your doctor to see what they may have. Different companies ware always giving stuff away to doctors. You will never know until you ask.
The most important thing you can do to keep costs low is to take care of yourself. Figure out a diet plan that works well for you and stick to it. Develop an exercise plan that you can do on a regular basis. See your doctor whatever you need to. Doing these things will help you cut down on costs, especially in the long run.
Eating Out Tips For Diabetics
Posted by admin in Prescription Diabetes Drugs, Weight Loss on April 28th, 2009
When you have diabetes, eating out can sometimes be a challenge. Here are some tips on how to eat out in a way that will not throw off your eating schedule or your blood glucose level.
First, stay on schedule. If you are on a tight meal schedule in order to maintain better diabetes management, make the dinner plans around your schedule. Make sure that your dinner partners know that with diabetes it is important that you eat at a certain time of day. It is even better if you can dine in a restaurant that is conveniently located.
Second, make a reservation. There is nothing worse than getting to a restaurant and being put on the “waiting list” when you have a meal schedule. The wait times at most mid- to high-end restaurants can be up to an hour. Avoid a long wait time by calling ahead. And always be sure to show up a few minutes early - most places will not hold your table more than 15 minutes if a large crowd is waiting.
Third, eat a snack. Have a piece of fruit of a small serving of carbohydrates before leaving your home. This will help your blood glucose level remain in the normal range if you do end up with a long wait at a restaurant. And always be sure and keep extra glucose and insulin on hand to control your highs and lows if you plan on being out for an extended period of time.
Fourth, limit your alcoholic beverages. Alcohol can have some profound effects on the blood glucose level of a diabetic. The safest thing is not to drink at all. But, if you do, make sure that you do not drink on an empty stomach, and test your blood glucose level often. The best way to know how alcohol will affect your blood glucose is to test at least every 30 minutes. And, again, make sure that you have plenty of fast-acting glucose and insulin on hand to combat the effects of alcohol on blood glucose levels.
And, finally, relax! As long as you follow these few simple tips, your eating out experience as a diabetic will be a positive one!