Posted by admin in Prescription Diabetes Drugs on July 16th, 2009

Combined aerobic and resistance training may offer significant synergistic and incremental improvement in glycemic control compared with either aerobic training or resistance training alone, a review suggests.

Previous trials and studies have documented benefits of aerobic exercise for glycemic control in people with Type 2 diabetes.

To determine how intensity of aerobic exercise, resistance training, and combined aerobic and resistance training affect glycemic control, a team led by Silvano Zanuso, from the University of Padua in Italy, conducted a literature review.

Interventions with more vigorous aerobic exercise programs resulted in greater reductions in glycated hemoglobin (HbA1c), greater increase in maximal oxygen uptake (VO2max), and greater increase in insulin sensitivity.

Regarding the effects of resistance training, the researchers write: “Considering the available evidence, it appears that resistance training could be an effective intervention to assist glycemic control, especially considering that the effects of this form of intervention as reported in the three major randomized controlled trials is comparable with that reported with aerobic exercise.”

They further comment: “There exists some controversy over whether the exercise-induced benefits of glucose and insulin control are a result of multiple single bouts of exercise or whether there is a chronic training benefit.”

Regarding combined exercise training, the researchers say that results indicate: “a combined program of strength and aerobic training could induce positive adaptations on glucose control, insulin action, muscular strength, and exercise tolerance.”

They add: “Combined exercise training resulted in an additional change in HbA1c that achieved statistical significance if compared with aerobic training alone and with resistance training alone.”

Writing in the journal Acta diabetologica, the researchers warn: “From this review, it is clear that no known studies have been conducted to address the efficacy of combined resistance and aerobic training program over the long term on a large group of patients with Type 2 diabetes.”

They also point out: “No studies have evaluated the effect of different exercise intensities on HbA1c, some selected physiological parameters (VO2max, maximal strength, flexibility) as well as on cardiovascular risk factors.”

MedWire (www.medwire-news.md) is an independent clinical news service provided by Current Medicine Group, a part of Springer Science+Business Media. © Current Medicine Group Ltd; 2009

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