The Brd2 gene is a promising new target in diabetes prevention. Researchers succeeded in preventing diabetes in high risk groups by inhibiting the expression (or activation) of the gene. Activating the gene seems to trigger sugar cravings and promote hunger, in order to meet the brain’s high energy demands.

It’s believed that the Brd2 gene is very active in high risk individuals. Influencing the activity of genes like Bdr2 is a promising new genetic target for diabetes prevention.

Researchers studying the gene concluded, “The strong influence of Brd2 on insulin resistance suggests that inhibiting Brd2 is a promising target for diabetes prevention and treatment.”

A New Field in Diabetes Prevention

The study of nutrients that influence gene expression is a promising new field in diabetes prevention, called nutrigenomics. It’s basically a natural form of gene therapy.

But unlike conventional gene therapy that chemically alters the DNA, nutrigenomics influences how a gene is expressed. Nutrients are used to turn genes on or off, depending on the desired effect. It’s a safe and effective method in disease prevention and treatment.

By inhibiting the Brd2 gene, nutrigenomics succeeds where conventional treatments fail…preventing sugar spikes, improving fasting glucose levels, and restoring insulin sensitivity.

How to Inhibit the Brd2 Gene

The best way to inhibit the Brd2 gene is to keep it turned off. This is possible if you avoid three metabolic states believed to activate the gene…

1. Fasting

Fasting for just 4 hours reduces the supply of constant energy required by the brain. The energy deficit activates the Brd2 gene leading to sugar cravings. This is why breakfast and eating several times throughout the day are so important.

2. Chronic Stress

Chronic stress saturates your body with adrenaline. The effect on the brain is dramatic. Brain cells start to fire like crazy, depleting energy supplies.

Needing more energy to manage the stress, the brain activates the Brd2 gene. This is why carbohydrates are comfort foods.

The quick energy that sugar provides keeps you level headed and helps you deal with the stress. But relief is temporary. Eating sugar eventually releases more adrenaline which further activates the Brd2 gene.

3. Systemic Inflammation

A typical Western diet is load with processed foods that damage cells and tissues, triggering inflammatory reactions. Systemic inflammation is a physical stress effecting the entire body.

The body responds to any type of stress by releasing adrenaline. As you learned about, adrenaline activates the Brd2 gene.

But it gets worse…

Inflammation prevents feeling “full.” Together with an active Brd2 gene, it keeps you hungry and craving dangerous carbohydrates.

Diabetes Prevention with Nutrigenomics

Target gene expression and protect against diabetes with nutrigenomics. Integrate the strategies below into your diabetic diet for preventing Brd2 gene activation.

1. Directly inhibit Brd2 activation with 200 mg/day of this potent antioxidant.

2. Learn the number of daily meals and healthy percentage of calories to avoid prolong fasting.

3. Learn when to eat breakfast (and what to eat) for breaking the overnight fast.

4. Supplement with green tea’s most powerful nutrient for stress relief.

5. Supplement twice a day with the most effective dose of omega-3 fats for easing inflammation.

6. Learn about the West African plant that controls hunger all day long.

7. Supplement with pine nuts for additional hunger control.

Have you been monitoring your blood sugar level for a while? Are you disturbed as your blood glucose levels are tricky? I know that a dangerous blood sugar level reading look fine if you have eaten several slices of cakes at your friend’s birthday party. However the things does not seem fine if you get a higher reading even after eating a low carb and high protein meal. What worse if the reading is high even after exercising the previous night?

If you are facing the same scenario then you must spend here few minutes to know what is actually going on within you. Let’s dig in to find out more.

I’m sure you know that exercise and diet affects the sugar level in blood. You may be unaware there are certain other things like virus or stress that affects the blood glucose level at the same time. A higher reading may also come up as with the regular usage and passage of time, your medication is no longer affecting your body system properly. A single higher reading is nothing that you should worry about. However if you notice a pattern or series of high readings then it is important to consult your health care professional.

It is the responsibility to check the sugar level in blood if you are a diabetic. Unluckily the monitoring of blood glucose level is like a two-edged sword. Studies have revealed that recurrent monitoring generally results in the feeling of “failure” or “success” for diabetics. If the results are becoming consistently higher then it may trigger the feeling of self blame and anxiety.

Sometimes these feelings cause some diabetics to give up blood glucose monitoring. The important here is to understand that blood glucose monitoring is not a test but a tool to fight against this deadly disease.

So if ever your blood glucose level results are higher you should

* Test again before meal and then two hours after meals. This will help you to check how well your medications are working for controlling the blood sugar level. It will also help you to understand which foods are boosting the levels of sugar in blood.

* Define the patterns of blood glucose readings. If the levels are higher one day then there isn’t any big deal. However repeated high levels of sugar in blood must be discussed with doctor.

* Start taking baby steps. Try some more exercise or limit the amount of carbohydrates in your next meal. Never go overboard. If ever a pattern is seen for more than three days consult your physician.

* Relaxing is best for controlling blood sugar levels. It is not only the food that converts blood glucose level in a roller coaster. If there are dangerous blood sugar levels on your glucometer then it is the right time to relax.

* Try to build a friendly relationship with your doctor. Even after doing all this you are unable to control blood sugar levels then discuss with your doctor. He is able to see the bigger picture. Sometimes with the passage of time the pancreatic cells stop to produce insulin, sometime the particular medicine becomes ineffective. Doctor’s suggestion can be of great help to you.

Diabetes Types and Causes

Posted by admin in Prescription Diabetes Drugs on April 30th, 2010

A group of diseases that affect how your body uses blood glucose is known as diabetes mellitus. Chronic conditions are type 1 and type 2 diabetes. The reversible conditions are gestational diabetes and pre-diabetes. Gestational diabetes occur during pregnancy and pre-diabetes is when your blood sugar levels are higher than normal but still not high enough to be classified as diabetes.

There is no known exact cause of type 1 diabetes known to scientists. It is proven that the immune system that protects and fights off harmful bacteria and viruses, mistakenly destroys the cells that produce insulin in the pancreas. This insulin is also known as islet. No matter what the cause of your diabetes, rather it be genetic or triggered by a virus, once the islet cells are destroyed, your body will produce little or no insulin. Type 1 diabetes was also known as juvenile diabetes although it usually appears during adolescence but can develop at any age.

If you have any type of diabetes, your blood has too much glucose. Glucose is vital because it is the body’s main source of energy that fuels your tissue and muscles.

Normally, cells get energy to the body’s muscles and tissues by getting glucose in them from the help of the hormone insulin. The pancreas produces insulin and is located just behind the stomach. When your body is working properly, after eating, insulin will secrete from the pancreas into your bloodstream. Then it circulates and acts like a key unlocking tiny doors that allow sugar to enter into cells. Insulin lowers the amount of sugar in the bloodstream dropping the sugar levels and the secretion from the pancreas.

Our livers act as a manufacturing center that stores glucose. If you haven’t eaten in a while, your insulin levels can get low triggering the liver to convert stored glycogen back to glucose to keep your levels within a normal range. This doesn’t occur with type 1 diabetes, there is no insulin to put glucose into your body’s cells. This causes sugar to build up in your bloodstream, when it should be transported to the cells. When this occurs, it can be life threatening.

The more familiar type 2 diabetes has a different cause. It was once known as adult-onset or non-insulin dependent diabetes, a chronic condition that affects the way your body metabolizes sugar. Islet cells still function, but the pancreas doesn’t produce enough insulin or it becomes resistant to it. There is no cure for type 1 or type 2 diabetes, but it is preventable and manageable. You can start with a healthy diet, exercising and maintaining your weight. You still may need insulin therapy or diabetes medications. Your weight and diet should always be managed, even if you are on medications or insulin.