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<channel>
	<title>Discuss Diabetes</title>
	<atom:link href="http://discuss-diabetes.com/feed/" rel="self" type="application/rss+xml" />
	<link>http://discuss-diabetes.com</link>
	<description>Diabetes Blog and Articles</description>
	<pubDate>Sat, 20 Mar 2010 09:00:16 +0000</pubDate>
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	<language>en</language>
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		<title>Best Home Diabetes Treatment</title>
		<link>http://discuss-diabetes.com/2010/03/best-home-diabetes-treatment/</link>
		<comments>http://discuss-diabetes.com/2010/03/best-home-diabetes-treatment/#comments</comments>
		<pubDate>Sat, 20 Mar 2010 09:00:16 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
		<category><![CDATA[Prescription Diabetes Drugs]]></category>

		<category><![CDATA[Blood Sugar Level]]></category>

		<category><![CDATA[Fatigue]]></category>

		<category><![CDATA[Human Body]]></category>

		<guid isPermaLink="false">http://discuss-diabetes.com/2010/03/best-home-diabetes-treatment/</guid>
		<description><![CDATA[This is about chronic disease deals with blood sugar in human body. According to research, diabetes has three types such as type 1, 2 and 3. This disease brings several symptoms to people. Sometimes it is like an ordinary ill and people disregard about it.
Nowadays, people can take a treatment at home. They can heal [...]]]></description>
			<content:encoded><![CDATA[<p>This is about chronic disease deals with blood sugar in human body. According to research, diabetes has three types such as type 1, 2 and 3. This disease brings several symptoms to people. Sometimes it is like an ordinary ill and people disregard about it.</p>
<p>Nowadays, people can take a treatment at home. They can heal their diabetes without visiting doctor as routine as you do. This is according to research by diabetes specialists. They work together to have contrivance to heal diabetes. Most of them are natural component.</p>
<p>Besides, you have to treat your meal in right portion; you have to know that many natural components are used to heal diabetes. For example, you can make fresh juice with Jambul fruit. It contain of glucoside that will control blood sugar level. It gives good effect to pancreas. You can take the seeds, dry it and start to make powder. You can take the powder to be mixed with your low fat milk.</p>
<p>Sometimes people use grapefruit to heal their diabetes. Actually, it has different taste with other oranges, but it has good advantages to reduce blood sugar effectively. Doctor also recommends this fruit to be eaten for maintaining patient.</p>
<p>I am sure that you know mango right? This is one of home treatment to heal diabetes. But, you have to know, you will not eat the fruit, but you will consume mango leaves as many as you can. You can swamp about 10-15 mango leaves into water, let it in a day then you take the essence. You can drink to heal your diabetes.</p>
<p>People may suffer when they have to feel sign of diabetes. They will get hard headache or fatigue, poor vision immediately, losing the weight drastically and so on. They must be aware earlier.</p>
<p>This is the best home treatment for this dangerous disease, you can take bitter gourd. It is more effective to reduce blood sugar level in your body. You can make a juice and drink it routinely every morning. Sooner or later you will get your blood sugar stable. You can try one of them to maintain this chronic disease.</p>
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		<item>
		<title>Diabetes Diet With Herbal Control</title>
		<link>http://discuss-diabetes.com/2010/03/diabetes-diet-with-herbal-control/</link>
		<comments>http://discuss-diabetes.com/2010/03/diabetes-diet-with-herbal-control/#comments</comments>
		<pubDate>Sat, 20 Mar 2010 07:00:50 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
		<category><![CDATA[Prescription Diabetes Drugs]]></category>

		<category><![CDATA[Exercises]]></category>

		<category><![CDATA[Insulin]]></category>

		<category><![CDATA[Leaves]]></category>

		<guid isPermaLink="false">http://discuss-diabetes.com/2010/03/diabetes-diet-with-herbal-control/</guid>
		<description><![CDATA[If the insulin in your body can&#8217;t be processed properly, you may walk into long life disease called diabetes. Diabetes as a long life disease needs special treatment to keep you able to do activities. Diabetes diet can also be found in a form of herbal thing.
The first herbal you can use is the leaves [...]]]></description>
			<content:encoded><![CDATA[<p>If the insulin in your body can&#8217;t be processed properly, you may walk into long life disease called diabetes. Diabetes as a long life disease needs special treatment to keep you able to do activities. Diabetes diet can also be found in a form of herbal thing.</p>
<p>The first herbal you can use is the leaves of Neem tree. This natural chemical can help you to regulate glucose level in your body by changing it into energy. But you also need to know how to use it on a regular basis. After Neem tree, you may want to consume fenugreek juice. You can take it in early morning when you have not eaten yet on a regular basis. This is effective to help diabetes remedies along with exercises.</p>
<p>Next herbal choices for your diet is Amla juice. Also on regular basis and regularly a day, it can help you to relief the disease. Amla juice can be found in the market easily so do not worry difficult to find this chemical.</p>
<p>Mango leaves may not popular for curing the disease but you can use it too. Leave few mango laves overnight in 250cc water. Then drink it in the morning in appropriate basis regularly.</p>
<p>Sweet potatoes leaves also can be beneficial for diabetes diet. It is helpful in regulating blood sugar so you can keep your body&#8217;s glucose level. It is also suggested to consume for people who feel any sign of diabetes in order to prevent it developed.</p>
<p>Diabetes commonly makes people have to go to bath frequently and excessive thirst. You may also feel hungry even you have already eat as much as usual. The long life disease with those symptoms are very unwanted occurs in our body. So we need to change our lifestyle to be healthier then we can prevent it to occur.</p>
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		<title>Recommended American Diabetes Diet</title>
		<link>http://discuss-diabetes.com/2010/03/recommended-american-diabetes-diet/</link>
		<comments>http://discuss-diabetes.com/2010/03/recommended-american-diabetes-diet/#comments</comments>
		<pubDate>Sat, 20 Mar 2010 07:00:21 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
		<category><![CDATA[Prescription Diabetes Drugs]]></category>

		<category><![CDATA[Absolute Cure]]></category>

		<category><![CDATA[Drastic Transformation]]></category>

		<category><![CDATA[Glucose Levels]]></category>

		<guid isPermaLink="false">http://discuss-diabetes.com/2010/03/recommended-american-diabetes-diet/</guid>
		<description><![CDATA[A healthy diet is very important to everyone. Especially for diabetics, a healthy and well controlled diet is highly recommended. Health experts in the United States have noted the importance of following a strict American diabetes diet. The type of food a diabetic eats can either be helpful or detrimental. Because it can turn out [...]]]></description>
			<content:encoded><![CDATA[<p>A healthy diet is very important to everyone. Especially for diabetics, a healthy and well controlled diet is highly recommended. Health experts in the United States have noted the importance of following a strict American diabetes diet. The type of food a diabetic eats can either be helpful or detrimental. Because it can turn out into a matter of life and death, an American diabetes diet is very crucial.</p>
<p>Diabetes refers to a health condition where a person&#8217;s body is unable to metabolize the glucose. A person also cannot efficiently maintain and control blood sugar levels as most people do. Previously, diabetes is a rare case. However, with the drastic transformation in the way people eat and what constitutes their diet, the condition is now prevalent. Nearly all parts of the world have their own case of diabetes. In different sectors and in almost every age range, there is a case of diabetes. Because of the alarming rates, health experts are continuously trying to mitigate, control and help people to deal with diabetes. The relevance of diet to a person&#8217;s health condition became extremely relevant in the treatment and management of diabetes. As diabetes has no absolute cure, following an American diabetes diet is the best thing to do.</p>
<p>The Ideal American diabetes Diet</p>
<p>Just like everyone else, a diabetic person also needs the same amount of nutrients each day. The only difference is that the type of food a diabetic eats should not increase blood sugar levels. Weight is also more controlled for diabetics. Whereas people generally need to take care of their weight, diabetics need to make sure their weight remains within the safe zone. Exercise is very important. Another difference of the American diabetes diet with the average diet is that it is tailored to match a diabetic medication. The diet, exercise and the medication all help maintain blood sugar levels. The control of the body&#8217;s glucose levels makes diabetes a more manageable health condition.</p>
<p>Calorie Limit</p>
<p>A diabetic diet usually has a calorie limit. For instance, there is the 1200 calorie diet and the 1800 calorie diet. Excluding foods that can trigger an increase in blood sugar levels, any food combination should do so long as the total calories for the whole day do not exceed 1200 or 1800. Some of the more common foods included in a diabetic diet include: cereals, vegetables, yogurt and a piece or two of fruit.</p>
<p>Alternative Sweeteners</p>
<p>Ideally, a diet for diabetics should be sugarless. Fortunately for technological and scientific advancements, there are now artificial sweeteners. These artificial sweeteners are designed to provide the same flavor as sugar does without the added calorie and glucose intake.</p>
<p>The most important thing in a diabetic diet is to keep glucose intake in check. To make sure that the diet is correct, it is necessary to consult a doctor and a professional nutritionist.</p>
<p>Please read more related topic: <a target="_new" rel="nofollow" href="http://www.diabeticdietplancenter.com/1800-Diabetic-Diet-Tips.php">1800 Diabetic-Diet Tips</a>.</p>
]]></content:encoded>
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		<item>
		<title>Identify Diabetic Symptoms and Get Ready to Fight</title>
		<link>http://discuss-diabetes.com/2010/03/identify-diabetic-symptoms-and-get-ready-to-fight/</link>
		<comments>http://discuss-diabetes.com/2010/03/identify-diabetic-symptoms-and-get-ready-to-fight/#comments</comments>
		<pubDate>Fri, 19 Mar 2010 09:00:21 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
		<category><![CDATA[Prescription Diabetes Drugs]]></category>

		<category><![CDATA[Dangerous Situation]]></category>

		<category><![CDATA[Heart Ailments]]></category>

		<category><![CDATA[Symptoms Of Diabetes]]></category>

		<guid isPermaLink="false">http://discuss-diabetes.com/2010/03/identify-diabetic-symptoms-and-get-ready-to-fight/</guid>
		<description><![CDATA[Are you at an increased risk of diabetes? If yes then it is religiously important for you to have this information. Diabetic symptoms can greatly help the individuals who are at an increased risk of diabetes. This will enable them to listen to their bodies the moment something goes wrong.
Let us start from the beginning
What [...]]]></description>
			<content:encoded><![CDATA[<p>Are you at an increased risk of diabetes? If yes then it is religiously important for you to have this information. Diabetic symptoms can greatly help the individuals who are at an increased risk of diabetes. This will enable them to listen to their bodies the moment something goes wrong.</p>
<p>Let us start from the beginning</p>
<p><u><strong>What Is Diabetes?</strong></u> Diabetes is an illness that takes place when the body either do not produce adequate amount of insulin or the body cells do not react efficiently to the provided insulin. It is a hormone that helps the body to break down glucose into energy. If the body of the person is unable to either produce or process insulin it puts extremely damaging effect to the vital body organs. Diabetes if left untreated may cause eye related problems, heart ailments, skin and kidney problems. In the extreme case the diabetic individual may enter into diabetic coma or even die.</p>
<p>There are many individuals who are at an increased risk of diabetes because of their genes. The diabetes runs in families. There are some individual who are caught by the disease because of sedentary lifestyle or some traumatic event. It is important to know that diagnosis of diabetes does not mean that it is the end of life. There are many celebrities as well as common people who lead a healthy happy life even with diabetes. Diabetes test is the best thing to diagnose this chronic ailment. However there are few symptoms that can help the diabetics to give an alarming signal that person is suffering from diabetes.</p>
<p><u><strong>Diabetic Symptoms:</strong></u> The symptoms of diabetes include</p>
<ul>
<li>Blurriness in vision</li>
<li>Tiredness</li>
<li>Sudden weight loss</li>
<li>Irritability and mood swings</li>
<li>Excessive thirst</li>
<li>Unquenchable thirst</li>
<li>Excessive hunger</li>
</ul>
<p>Mostly people ignore these early signs of diabetes as they look so harmless. This ignorance may cause them to suffer from undiagnosed diabetes sometimes even for years. This is a dangerous situation. The diabetic symptoms continue to get worse and end in chronic life threatening complications.</p>
<p>However it is equally important here not to misdiagnose yourself. Many signs of diabetes signal one or some other sign of disease. In simpler words one must not consider himself diabetic, if he is feeling tired or thirsty. Sometimes these signs of diabetes could because of being dehydrated.</p>
<p>If more than one symptom appears for a longer period of time it is good to have it tested. Even if you are not yet diagnosed with diabetes but if you are at an increased risk of diabetes it is good to go for regular diabetes screening.</p>
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		<title>What Does Lack of Sleep Do to Your Blood Sugar Levels?</title>
		<link>http://discuss-diabetes.com/2010/03/what-does-lack-of-sleep-do-to-your-blood-sugar-levels/</link>
		<comments>http://discuss-diabetes.com/2010/03/what-does-lack-of-sleep-do-to-your-blood-sugar-levels/#comments</comments>
		<pubDate>Fri, 19 Mar 2010 07:00:53 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
		<category><![CDATA[Prescription Diabetes Drugs]]></category>

		<category><![CDATA[Blood Sugar Levels]]></category>

		<category><![CDATA[Diabetics]]></category>

		<category><![CDATA[Sleep Apnea]]></category>

		<guid isPermaLink="false">http://discuss-diabetes.com/2010/03/what-does-lack-of-sleep-do-to-your-blood-sugar-levels/</guid>
		<description><![CDATA[When people with type 2 diabetes are advised on how to control their diabetes&#8230; the type of food they eat and the amount of exercise they should do each week, predominates in the conversation. Up until now sleep is usually not mentioned but according to research, sleep might be another important factor.
A study at the [...]]]></description>
			<content:encoded><![CDATA[<p>When people with type 2 diabetes are advised on how to control their diabetes&#8230; the type of food they eat and the amount of exercise they should do each week, predominates in the conversation. Up until now sleep is usually not mentioned but according to research, sleep might be another important factor.</p>
<p>A study at the <em>University of Chicago</em> looked at sleep and glucose tolerance in eleven non-diabetic people, average age 40, who were overweight and under-exercised. They averaged slightly less than eight hours of sleep each night.</p>
<p>
<ul>
<li>for fourteen nights they were allowed to sleep for eight and a half hours, and</li>
<li>for fourteen nights they were allowed to sleep only five and a half hours</li>
<li>no exercise was permitted, and</li>
<li>junk food was provided</li>
</ul>
<p>During the two weeks of being sleep deprived, the volunteers had higher blood sugar levels and showed less sensitivity to insulin.</p>
<p>Another study at the same institution found similar results in younger, leaner volunteers. Nine people between the ages of 21 and 30 were allowed to sleep for eight and half hours for three nights in the lab. When the subjects went into deep sleep, sound was used to make them sleep more lightly. A glucose tolerance test was given and blood insulin levels were measured. It was found that sensitivity to insulin decreased by 25 per cent. In eight of the subjects, insulin production did not increase, causing their blood sugars to rise by 23 per cent.</p>
<p>Sleep apnea, or stoppage of breathing for 10 seconds or more during sleep, is common among diabetics. About 40% of men with type 2 diabetes also suffer sleep apnea, and that number goes up to 61 per cent for men over 65.</p>
<p>Lack of sleep or at least deep sleep, may cause imbalances in substances like catecholamines and the hormone cortisol in your body. Catecholamines and cortisol prepare your body for the &#8216;fight or flight&#8217; response, and one way they do this is by raising the blood sugar level. This is one possible mechanism for a connection between lack of quality sleep and type 2 diabetes.</p>
<p>Like type 2 diabetes, sleep apnea is a disorder that people who have it, often don&#8217;t recognize.</p>
<p><strong> Symptoms include</strong>:</p>
<p>
<ul>
<li>tiredness</li>
<li>waking up tired</li>
<li>lack of energy</li>
<li>headaches, and</li>
<li>falling asleep without trying to, such as when reading or watching television.</li>
</ul>
<p>A lack of quality sleep places you at an increased risk of several health problems. If you are type 2 diabetic it will make weight loss and control of your blood sugar levels much more difficult. Not getting enough sleep on a regular basis makes your body less sensitive to insulin which puts you at an increased risk of weight gain.</p>
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		<title>What Type 2 Diabetics Need to Know About Coffee, Tea, and Antioxidants!</title>
		<link>http://discuss-diabetes.com/2010/03/what-type-2-diabetics-need-to-know-about-coffee-tea-and-antioxidants/</link>
		<comments>http://discuss-diabetes.com/2010/03/what-type-2-diabetics-need-to-know-about-coffee-tea-and-antioxidants/#comments</comments>
		<pubDate>Fri, 19 Mar 2010 07:00:24 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
		<category><![CDATA[Prescription Diabetes Drugs]]></category>

		<category><![CDATA[Importance Of Fruits And Vegetables]]></category>

		<category><![CDATA[Journal Of Nutrition]]></category>

		<category><![CDATA[Oxford Brookes University]]></category>

		<guid isPermaLink="false">http://discuss-diabetes.com/2010/03/what-type-2-diabetics-need-to-know-about-coffee-tea-and-antioxidants/</guid>
		<description><![CDATA[For all the hoopla about the importance of fruits and vegetables in the diet, for most diabetics and for the public in general the single greatest daily source of antioxidants is coffee and tea. New research from the UK, however, reports that adding milk or cream to tea has substantial impact on the availability of [...]]]></description>
			<content:encoded><![CDATA[<p>For all the hoopla about the importance of fruits and vegetables in the diet, for most diabetics and for the public in general the single greatest daily source of antioxidants is coffee and tea. New research from the UK, however, reports that adding milk or cream to tea has substantial impact on the availability of its antioxidants.</p>
<p><strong>Improved Blood Sugar Levels:</strong> The catechins in tea have been linked to improvements in the control of blood sugar levels as well as to lowering the risk of cancer, type 2 diabetes, and Alzheimer&#8217;s disease. Green (unfermented) tea contains 30 to 40 per cent catechins by weight, while black (fermented) tea still contains 3 to 10 per cent catechins. Both green tea and black tea are important as sources of catechins and other antioxidants in diets throughout the world. Black tea is especially important in the English-speaking world, primarily as iced tea in America, and primarily as hot tea in other countries.</p>
<p><strong>Adding milk to tea:</strong> Lisa Ryan and Sebastien Petit of the <em>Functional Food Center at Oxford Brookes University</em> report findings that adding any kind of milk to tea (hot or cold) lowers the available antioxidant content by about 7 per cent. Adding skim milk to tea<strong>,</strong> however, lowers the available antioxidant content by about 25 per cent. This finding adds to previous research advising against the addition of milk to tea. In 2007 scientists at the <em>Charite Hospital in Berlin</em> reported that straight black tea opens arteries to the heart and helps lower blood pressure, but that proteins in milk added to tea cancel out this benefit.</p>
<p><strong>Adding milk to coffee:</strong> Scientists have also looked at the effects of adding milk and cream to coffee. In 2009 researchers at the food giant Nestle reported in the<em> Journal of Nutrition</em> that adding milk or cream to coffee had no effect on the availability of the antioxidant isoferulic acid, ferulic acid, or caffeic acid from the beverage. Adding non-dairy creamer and sugar to instant coffee, however, made the heart-healthy and cancer-preventative antioxidants unavailable.</p>
<p><strong>Higher Blood Sugar Levels:</strong> Coffee also contains large amounts of the antioxidant chlorogenic acid&#8230; this is what helps give coffee its flavor, and magnesium. Both of these improve insulin sensitivity and therefore reduces the risk of developing type 2 diabetes.</p>
<p>If you already have type 2 diabetes though, the news isn&#8217;t so good. Coffee raises your blood sugar level in the short term, and if you have already been diagnosed with type 2 diabetes, drinking coffee makes it much more difficult for you to control your blood sugar levels and to also lose weight.</p>
<p>If you drink coffee it is best to only drink two cups each day&#8230; without the non-dairy creamer and sugar!</p>
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		<title>Natural Support For Diabetic Nerve Pain</title>
		<link>http://discuss-diabetes.com/2010/03/natural-support-for-diabetic-nerve-pain/</link>
		<comments>http://discuss-diabetes.com/2010/03/natural-support-for-diabetic-nerve-pain/#comments</comments>
		<pubDate>Thu, 18 Mar 2010 09:00:18 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
		<category><![CDATA[Prescription Diabetes Drugs]]></category>

		<category><![CDATA[3 Fatty Acids]]></category>

		<category><![CDATA[Blood Glucose]]></category>

		<category><![CDATA[Nerve Cell Membranes]]></category>

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		<description><![CDATA[You can stop the pain and improve your quality of life by supplementing with specific nutrients proven to support healthy nerves. Add the following nutrients to your current treatment regimen and experience for yourself the healing power of food.
1. Acetyl-L-Carnitine (ALC)
ALC is an amino acid that increases energy production by supplying nerve cells with fatty [...]]]></description>
			<content:encoded><![CDATA[<p>You can stop the pain and improve your quality of life by supplementing with specific nutrients proven to support healthy nerves. Add the following nutrients to your current treatment regimen and experience for yourself the healing power of food.</p>
<p>1. Acetyl-L-Carnitine (ALC)</p>
<p>ALC is an amino acid that increases energy production by supplying nerve cells with fatty acids. The more energy a nerve cell can produce, the better it can regenerate and function.</p>
<p>Supplementing with it has been shown to improve pain and physical strength in diabetics. All it takes is a daily dose of 1000 mg taken on an empty stomach to stop the pain.</p>
<p>2. Lipoic Acid</p>
<p>Lipoic acid is a powerful antioxidant found in leafy green vegetables and dark colored fruits. It is recognized by herbalist as a powerful nutrient for prevention of diabetes complications, including nerve damage.</p>
<p>Diabetic patients treated with 600 mg for 60 days showed significant improvements in reported pain from peripheral neuropathy. The &#8220;R&#8221; type of lipoic acid was used in the study. This is the active form preferred by the body.</p>
<p>3. Pregnenolone</p>
<p>Pregnenolone is best known as the &#8220;mother&#8221; hormone because it&#8217;s the precursor to all steroids such as testosterone and estrogen. However, it was first identified as a neuro-active steroid that is essential to the structure of nerve cell membranes.</p>
<p>This is important to diabetics because blood glucose damages cell membranes and disrupts normal communication between nerve cells. The structural damage to nerve cell membranes results in chronic pain and debilitation.</p>
<p>Pregnenolone can help repair and regenerate cell membranes. For most diabetics, the effective dose is between 50 to 100 mg/day.</p>
<p>4. Omega-3 Fats</p>
<p>Nerve endings require specific types of unsaturated fats called omega-3 fatty acids. Found in cold-water fish, the omega-3 fats insulate nerves and help conduct electrical signals.</p>
<p>Studies have shown that omega-3 fats are able to reduce nerve damage caused by high blood sugar and reduce pain. Take 4000 mg/day of omega-3 fats.</p>
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		<title>Research on Whether Depression is More Common in Type 2 Diabetics Or Not!</title>
		<link>http://discuss-diabetes.com/2010/03/research-on-whether-depression-is-more-common-in-type-2-diabetics-or-not/</link>
		<comments>http://discuss-diabetes.com/2010/03/research-on-whether-depression-is-more-common-in-type-2-diabetics-or-not/#comments</comments>
		<pubDate>Thu, 18 Mar 2010 07:00:46 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
		<category><![CDATA[Prescription Diabetes Drugs]]></category>

		<category><![CDATA[Counting Numbers]]></category>

		<category><![CDATA[Jaipur India]]></category>

		<category><![CDATA[Psychological Status]]></category>

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		<description><![CDATA[All around the world, hundreds of millions of people face long bouts of major depression. For many people, life conditions are depressing, but for up to 48% of diabetics, the underlying cause of depression may be poorly regulated blood sugar levels.
Depression is thought to be twice as common in diabetics as in the population generally. [...]]]></description>
			<content:encoded><![CDATA[<p>All around the world, hundreds of millions of people face long bouts of major depression. For many people, life conditions are depressing, but for up to 48% of diabetics, the underlying cause of depression may be poorly regulated blood sugar levels.</p>
<p>Depression is thought to be twice as common in diabetics as in the population generally. Different factors can contribute to the development of depression and includes:</p>
<p>
<ul>
<li>emotions</li>
<li>environmental factors</li>
<li>biology</li>
</ul>
<p>Scientists at the diabetes specialty clinic at the <em>SMS Hospitals in Jaipur, India</em> studied fifty adults who had type 2 diabetes and a control group of thirty adults who were diabetes-free. They excluded anyone who had a previous history of depression or any other psychiatric illness, history of addiction or substance, high blood pressure, or any medical condition except diabetes. (The volunteers in the control had none of these conditions.) Using a standard psychological exam for measuring depression, the researchers then assessed the psychological status of the eighty people in the study.</p>
<p><strong>The researchers found that 46% of the type 2 diabetics in this study suffered depression.</strong> Of all the diabetics in the study:</p>
<p>
<ul>
<li>12% were were suffering from mild depression</li>
<li>16% from moderate depression, and</li>
<li>18% from severe depression</li>
</ul>
<p>There was a trend suggesting higher blood sugars tracked to the most severe depression, but the study group was too small to establish definitive statistics. The average fasting blood sugar level in the type 2 diabetics who did not display depression was 123 mg/dL (6.8 mmol/L). The average fasting blood sugar level among the diabetics who had depression was 151 mg/dL (8.4 mmol/L).</p>
<p><strong>Researchers also tested mental skills in both groups</strong>. Diabetics did not do as well as non-diabetics. Diabetics did worse than non-diabetics on every measure of mental ability the researchers tested but especially in tests that involved:</p>
<p>
<ul>
<li>counting numbers forwards</li>
<li>counting numbers backwards, and</li>
<li>recognizing symbols</li>
</ul>
<p>Diabetics did relatively well in tests that required the use of language, but relatively poorly in tests that required the ability to learn new information quickly. There was no clear-cut relationship between depression and other forms of mental decline.</p>
<p><strong>The researchers admitted that they had not studied enough people to reach definitive,</strong> sweeping conclusions. This and other studies, however, suggest that keeping blood sugar levels down goes a long way toward keeping mental faculties sharp.</p>
<p>Although this study showed 46% of those tested suffered some degree of depression, it also showed that lower blood sugar levels gave a lesser degree and chance of depression. Unfortunately depression makes people less motivated to eat healthy foods and to exercise, which means higher blood sugar levels.</p>
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		<link>http://discuss-diabetes.com/2010/03/724/</link>
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		<pubDate>Thu, 18 Mar 2010 07:00:19 +0000</pubDate>
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		<category><![CDATA[Prescription Diabetes Drugs]]></category>

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		<description><![CDATA[Tight control of systolic blood pressure (SBP) to a target of less than 130 mmHg in diabetics with coronary artery disease (CAD) does not significantly reduce the incidence of cardiovascular (CV) events compared with usual control, and is associated with increased all-cause mortality, shows an analysis of INVEST.
In INVEST (International Verapamil SR ??&#8221; trandolapril Study), [...]]]></description>
			<content:encoded><![CDATA[<p>Tight control of systolic blood pressure (SBP) to a target of less than 130 mmHg in diabetics with coronary artery disease (CAD) does not significantly reduce the incidence of cardiovascular (CV) events compared with usual control, and is associated with increased all-cause mortality, shows an analysis of INVEST.</p>
<p>In INVEST (International Verapamil SR ??&#8221; trandolapril Study), patients with diabetes and CAD were randomly assigned to receive antihypertensive therapy with either a calcium-channel blocker or a beta blocker, plus an ACE inhibitor and/or a thiazide diuretic. In extended follow-up of 6400 patients enrolled in the trial, those who achieved SBPs lower than 130 mmHg had cardiovascular outcomes equivalent to those who achieved SBPs between 130 and 140 mmHg.</p>
<p>But a subanalysis of 5077 patients from the USA showed that the tight BP control strategy was associated with an adjusted hazard ratio (HR) of 1.15 (p=0.036) for all-cause mortality compared with usual control, defined as a SBP lower than 140 mm Hg.</p>
<p>&#8220;We wonder whether it&#8217;s time to rethink lower BP goals in patients with diabetes and CAD,&#8221; said Rhonda Cooper-DeHoff from the University of Florida in Gainesville, Florida, USA, who presented the data during a late-breaking clinical trials session at the 2010 annual scientific sessions of the American College of Cardiology in Atlanta, Georgia, USA.</p>
<p>The findings appear to contravene the position of the <a href="http://www.diabetes.org/" rel="nofollow">American Diabetes Association</a>, which has previously issued a position statement saying that &#8220;there is no threshold value for BP [in diabetics], and risk continues to decrease well into the normal range.&#8221;</p>
<p>INVEST was designed to determine whether lowering SBP below 130 mmHg could provide additional CV benefits, particularly among diabetic patients with CAD. The international trial enrolled 22,576 patients with CAD and hypertension, and randomly assigned them to receive either verapamil SR plus trandolapril and the thiazide diuretic hydrochlorothiazide [HCTZ], or atenolol plus HCTZ and trandolapril. Trandolapril was recommended for all diabetic patients in the study.</p>
<p>The analysis focused on mortality rates among a US cohort of diabetic patients followed for an extended period, from September 1997 through November 2008. To evaluate the effects of very low SBP, the authors further categorized on-treatment SBP in increments of 5 mmHg.</p>
<p>During the extended follow-up period of 22,700 patient-years, the investigators found that, as predicted, patients whose BP was not controlled on therapy had an approximately 50% higher risk for a composite endpoint of death, nonfatal myocardial infarction (MI) or nonfatal stroke compared with those in the usual-control group. There were no significant differences between the tight- or usual-control groups with regard to either nonfatal MI of nonfatal stroke.</p>
<p>But in a Cox regression analysis of all-cause mortality, both the 110 to less than 115 mmHg and the less than 110 mmHg SBP categories were associated with increased risk for death. Other factors associated with increased mortality risk were age, race, peripheral arterial disease, coronary heart failure, US residency, renal impairment, left-ventricular hypertrophy, and transient ischemia.</p>
<p>MedWire (www.medwire-news.md) is an independent clinical news service provided by Current Medicine Group, a trading division of Springer Healthcare Limited. © Springer Healthcare Ltd; 2010</p>
<p><a href="http://acc10.acc.org/Pages/ACC2010Home.aspx" target="_blank" class="date">Meeting website</a></p>
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		<link>http://discuss-diabetes.com/2010/03/723/</link>
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		<pubDate>Wed, 17 Mar 2010 16:34:09 +0000</pubDate>
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		<description><![CDATA[Intensive blood pressure (BP) control does not reduce the rate of cardiovascular (CV) events in patients with Type 2 diabetes and high CV risk, reveals research presented at the 59th Annual Scientific Sessions of the American College of Cardiology in Atlanta, Georgia, USA.
The Action to Control Cardiovascular Risk in Diabetes (ACCORD) Blood Pressure trial found [...]]]></description>
			<content:encoded><![CDATA[<p>Intensive blood pressure (BP) control does not reduce the rate of cardiovascular (CV) events in patients with Type 2 diabetes and high CV risk, reveals research presented at the 59th Annual Scientific Sessions of the American College of Cardiology in Atlanta, Georgia, USA.</p>
<p>The Action to Control Cardiovascular Risk in Diabetes (ACCORD) Blood Pressure trial found that targeting therapy in such patients to achieve a systolic blood pressure (SBP) below 120 mmHg did not significantly reduce the annual rate of a composite of nonfatal myocardial infarction, nonfatal stroke, or death from CV causes, compared with a standard blood pressure target of below 140 mmHg.</p>
<p>A total of 4733 patients aged an average of 62.2 years with Type 2 diabetes were randomly assigned to intensive BP control (n=2362) or standard BP control (n=2371). The patients had an average baseline SBP of 139 mmHg, ranging from 130 to 180 mmHg, and had stable diabetes for at least 3 months, with a HbA1c of 7.5% to 11.0%. Also, 33.7% of patients had CV disease (CVD), while the remainder had subclinical CVD or at least two risk factors.</p>
<p>Patients in the intensive group were initiated on a two-drug therapy, typically a thiazide-type diuretic plus ACE inhibitor, angiotensin receptor blocker, or beta blocker. Drugs were then added and/or titrated at monthly visits to achieve the target SBP of 120 mmHg. In the standard group, therapy was intensified if SBP was 160 mmHg or above at the first visit or 140 mmHg or above at the second visit.</p>
<p>William Cushman, from the Veterans Affairs Medical Center in Memphis, Tennessee, USA, noted that &#8220;the SBP separated very early.&#8221;</p>
<p>He reported that BP from a year onward averaged at about 134 mmHg for the standard therapy group and at about 119 mmHg for the intensive therapy group.</p>
<p>This meant that, on average, a delta difference in BP of 14 mmHg was achieved from 1 year to the end of the 4.7-year study, which Cushman said was &#8220;certainly far greater&#8221; than the 10 mmHg minimum that they had set out to achieve.</p>
<p>Patients in the intensive treatment group took more drugs over the course of the study than did those in the standard treatment group, at an average number of 3.4 versus 2.1. Despite the difference in SBP, the patients receiving intensive BP-lowering therapy had a similar risk for the primary outcome as patients receiving standard therapy, at rates of 1.87% and 2.09%, respectively, and a hazard ratio of 0.88 (p=0.20).</p>
<p>The findings, published simultaneously advance online by the <i>New England Journal of Medicine</i>, did show about a 40% reduction in the risk for stroke in the intensive therapy group compared with the standard therapy group, however. And although this finding is consistent with meta-analyses summarizing the impact of a 10-mmHg reduction in SBP on stroke in observational studies, Cushman pointed out that the overall rate of stroke was very low, at about 0.5% per year.</p>
<p>&#8220;Therefore, although intensive management did significantly reduce total stroke and nonfatal stroke, assuming that this finding is real… the number needed to treat to lower the SBP to prevent one stroke over 5 years was 89.&#8221;</p>
<p>Cushman cautioned that patients receiving intensive therapy were also at increased risk for complications attributed to antihypertensive treatment compared with those receiving standard therapy, with occurrences seen in 3.3% versus 1.3% of patients. But overall serious adverse events were of a low order.</p>
<p>He concluded: &#8220;The results find no conclusive evidence that the intensive BP control strategy reduces the rate of a composite of major CV events, which was all-cause or fatal CV events plus nonfatal myocardial infarction and nonfatal stroke in high-risk adults with Type 2 diabetes.&#8221;</p>
<p>MedWire (www.medwire-news.md) is an independent clinical news service provided by Current Medicine Group, a trading division of Springer Healthcare Limited. © Springer Healthcare Ltd; 2010</p>
<p><a href="http://content.nejm.org/cgi/content/full/NEJMoa1001286" target="_blank" class="date">Free full text</a></p>
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